In the lung, increased LCN2 expression has been reported in subclinical pulmonary emphysema (11), chronic obstructive pulmonary disease (COPD) (12, 13), acute respiratory distress syndrome (ARDS) (14), as well as in patients with influenza A and SARS-CoV-2 virus infections (15). The gene discussed is LCN2; the disease is acute respiratory distress syndrome.