The vWF activity-antigen ratio was significantly lower in patients of the male sex, with non-O blood type, who are non-smokers, who do not consume coffee, with a fistula on the non-dominant arm, with no history of fistula interventions, and with no history of cardiovascular disease, DM, liver disease, antiplatelet use, or HMG-CoA reductase inhibitor use. This evidence concerns the gene VWF and cardiovascular disorder.