First, the results of univariate Cox regression analysis showed that BUB1 (HR: 3.576, 95% CI: 2.14063-5.97377, P<0.001), FDX1 (HR: 0.4046, 95% CI: 0.22222-0.73668, P= 0.00308), RPL3 (HR: 0.5724, 95% CI: 0.34249-0.95663, P=0.03324), T stage (HR: 2.2366, 95% CI: 1.31427-3.80621, P=0.003) and N stage (HR: 2.65774, 95% CI: 1.13725-6.21111, P=0.02401) were significantly associated with thyroid cancer prognosis (Figure 5A). This evidence concerns the gene BUB1 and thyroid gland carcinoma.