Compared with normal thyroid tissue, 7 CRGs were more highly expressed in thyroid cancer, namely BUB1 (P<0.001), RPL3 (P<0.001), TTK (P<0.001), GINS2 (P<0.001), SLC26A6 (P<0.001), CDKN2A (P<0.001) and ZNHIT2 (P<0.001). The gene discussed is CDKN2A; the disease is thyroid gland carcinoma.