The prevalence of thyroid disorders in adults were as follows: 1.20% of clinical hyperthyroidism, 0.2% of subclinical hyperthyroidism, 1.00% of clinical hypothyroidism, 29.20% of subclinical hypothyroidism, 9.80% of positive TPO Ab, 9.20% of positive TG Ab, 2.10% of goiter, 6.40% of single thyroid nodules and 1.80% of multiple nodules. The gene discussed is TPO; the disease is thyroid nodule.