The detection rates of subclinical hypothyroidism, and goiter were significantly higher in females (35.28%, 3.39%) than those in males (23.58%, 0.96%) (P < 0.05), and the positive rates of TPO Ab and TG Ab were significantly higher in females (13.54%, 13.94%) (P < 0.05). The gene discussed is TPO; the disease is goiter.