The GO category “positive regulation of inflammatory response, apoptotic process, positive regulation of interleukin-6 production, positive regulation of macrophage activation, positive regulation of tumor necrosis factor production, positive regulation of necroptotic process, T cell homeostasis” indicated that the genes were involved in processes of immune regulation, which fits well with the concept of PCOS as a chronic inflammatory disease. The gene discussed is TNF; the disease is polycystic ovary syndrome.