The results exhibited that the expression of BCL2 (FC = 1.35 & 1.52), PYGM (FC = 1.38 & 2.08) and TNFSF10 (FC = 1.42 & 1.73) was significantly higher in the GCs from PCOS patients and ovarian tissues of PCOS mice compared with controls. The gene discussed is PYGM; the disease is polycystic ovary syndrome.