FMR1 and fragile X syndrome: Decoding of sensory information by downstream regions may be impaired by abnormal activity correlations across areas, which have been observed in Shank3 null macaques and in humans with ASD (207, 208), and abnormal gamma rhythms, as observed in Fmr1 and Cntnap2 null mice and in people with fragile X syndrome (104, 144, 145, 180, 209).