Furthermore, several studies on other PD-causing proteins have reported reduced ERMCS in iPSC-derived dopaminergic neurons with triplication of the α-synuclein gene (Paillusson et al., 2017), PINK1 or DJ-1 knockdown neuroblastoma cells (Parrado-Fernández et al., 2018), and DJ-1 knockout neuroblastoma cells (Liu et al., 2019). The gene discussed is PINK1; the disease is Parkinson disease.