Fibronectin 1 (FN1), which is highly expressed by GGN macrophages (Figure 6C), could form complexes with integrin subunits of other cells (FN1_α2β1 complex, FN1_α3β1 complex, FN1_α4β1 complex, FN1_α5β1 complex) (Figure 6D), which promoted cancer cell migration through adhesion (Huaman and Ogunwobi, 2020). Here, FN1 is linked to cancer.