In the areas of breast and ovarian cancer, CAF subtypes have been defined based on multicolor flow cytometry yielding the four subtypes depending on how they stained for the fibroblast markers FAP, CD29, αSMA, S100-A4, PDGFRβ, and CAV1, accumulating differently in different tumors (Costa et al., 2018; Givel et al., 2018). The gene discussed is ACTA1; the disease is ovarian cancer.