Hu et al., having previously proposed mammalian sterile 20-like kinase 1 (Mst1) to be a key regulatory protein of autophagy and apoptosis in DCM, attempted to characterize whether or not the protein was involved in the pathology as an exosomal component (Lin et al., 2016; Zhang et al., 2016; Zhang M. et al., 2017; Hu et al., 2018). This evidence concerns the gene MST1 and familial dilated cardiomyopathy.