PPARG and type 2 diabetes mellitus: Studies of other pathways implicated in T2DM in diabetic mice models found that exosomal miR-155 induced glucose through the targeting of PPARγ and that healthy mice could develop T2DM through the introduction of miR-122, miR-192, miR-27a-3p, and miR-27b-3p; which collectively downregulated PPARα (Ying et al., 2017; Castaño et al., 2018).