INS and Hypoglycemia: Basal insulin delivery is shut off when the predicted or actual CGM value reaches a pre-specified hypoglycemia threshold and may remain suspended for a fixed time interval (Basal-IQ, 640G), may stay suspended until the CGM glucose value starts to rise (Basal-IQ), or a future predicted BG is above a pre-specified threshold (Basal-IQ, 640G) depending on the system [100,101].