The nomogram model based on six independent risk factors including age, heart rate (HR), hypertension, smoking history, Alanine aminotransferase (ALT), and Killip class, demonstrated excellent discrimination with an AUC of 0.84 (95% CI: 0.78–0.89), predicted C-index of 0.84 and curve fit of 0.713. This evidence concerns the gene GPT and Hypertension.