The similar antitumor function of statin on ALL cells, characterized by cell-cycle arrest, and induction of apoptosis mainly by upregulating BAX, p21, and p27 cells and downregulating cyclin D1, BCL-2, and p-Akt expression, has also been documented in another study (Wang et al., 2018). The gene discussed is AKT1; the disease is acute lymphoblastic leukemia.