CD8A and neoplasm: Neutrophil, Treg, CD8+ T cell, macrophages M1 and M2, cancer associated fibroblasts, myeloid dendritic cell, as well as activated mast cell had remarkably higher infiltrated levels within Mcluster B. CD8+ T cells can recognize and eliminate tumor cells through multiple mechanisms (Borst et al., 2018; Terrén et al., 2019; Philip and Schietinger, 2022).