The cGAS-STING pathway has been reported to strongly evoke IFN responses and effectively inhibit infection by several other RNA viruses, such as chikungunya virus (CHIKV) (Webb et al., 2020), encephalomyocarditis virus (EMCV) (Cui et al., 2020), hepatitis C virus (HCV) (Yi et al., 2016), murine norovirus (MNV) (Yu et al., 2021), Nipah virus (NiV) (Iampietro et al., 2021), and Zika virus (ZIKV) (Liu and Cherry, 2019). The gene discussed is CGAS; the disease is infection.