Subsequently, several studies demonstrated increased serum autoantibodies levels in glaucoma patients compared to healthy individuals, which included antibodies against HSP60 (Wax et al., 1998; Tezel et al., 2000), HSP70 (Joachim et al., 2007), and HSP27 (Tezel et al., 2000; Grus et al., 2004). This evidence concerns the gene HSPB1 and glaucoma.