TRPV1 expression is enhanced in the hippocampus of rats and the dentate gyrus of mice with temporal lobe epilepsy, as well as in the brains of individuals with temporal lobe epilepsy (Bhaskaran and Smith, 2010; Sun et al., 2013; Saffarzadeh et al., 2015). The gene discussed is TRPV1; the disease is temporal lobe epilepsy.