EGFR and glioblastoma: A previous study showed no difference in EGFR amplification or PTEN loss between SVZ and non-SVZ GBMs in 26 newly diagnosed IDH wild-type GBM cases.32 This study showed that the frequency of EGFR amplification in IDH wild-type GBM was 46% (12/26) and that of PTEN loss was 69% (18/26).