BACE1 and ischemia: Although we did find significant changes in the number of carbons and the number of double-bonds in total PC (Figures 6B–D), we detected that the silencing of BACE1 alone on ischemia or dual BACE1-SCD1 gene silencing in sham or ischemic groups significantly increased the concentration of carbons and mainly the number of unsaturations in the LPC class (Figures 6B, C).