Although we did find significant changes in the number of carbons and the number of double-bonds in total PC (Figures 6B–D), we detected that the silencing of BACE1 alone on ischemia or dual BACE1-SCD1 gene silencing in sham or ischemic groups significantly increased the concentration of carbons and mainly the number of unsaturations in the LPC class (Figures 6B, C). The gene discussed is SCD; the disease is ischemia.