AKT1 and rheumatoid arthritis: Based on our analyses, the aforementioned DMGs were significantly enriched in GO terms associated with hydrolase activity, actin filament, muscle cell proliferation, and antigen receptor-mediated signaling pathway, as well as KEGG pathways, such as, viral carcinogenesis, rheumatoid arthritis, Pl3k-Akt signaling, and MAPK signaling (Figures 2A–D).