TJP1 and myalgic encephalomeyelitis/chronic fatigue syndrome: ROC curve analysis for ME/CFS showed that compared to the reference, anti-β-LGB (AUC = 0.943; 95% CI: 0.86-1.00; P < 0.0001), ZO-1 (AUC = 0.934; 95% CI: 0.86-1.00; P < 0.0001), LPS (AUC = 0.806; 95% CI: 0.68-0.93; P < 0.0001), and sCD14 (AUC = 0.794; 95% CI: 0.68-0.92; P < 0.0001) were able to distinguish between ME/CFS patients and healthy controls as demonstrated by the AUC values using a univariate model (Figures 4A-E).