Among 23 proteins which increased in iLN group than SLE group, 19 proteins including ORM1 and SERPINC1 showed a protein interaction network related to acute phase response (FDR 8E-06), cellular oxidant detoxification (FDR 8E-03) and response to stress (FDR 4E-02) (Figure 1B). This evidence concerns the gene SERPINC1 and systemic lupus erythematosus.