STING1 and neoplasm: Compared with PD-L1-TIMEs (tumor-immune microenvironments), PD-L1+ stromal and intraepithelial TIMEs were highly enriched in IDO-1, HLA-DR, CD40, and CD163 and also showed spatially specific changes in CTLA-4, interferon gene stimulator (STING), and fibulin.