CD27, CD3, CD4, CD44, CD45, CD45RO, CD68, and CD163 are significantly enriched in the microenvironment of non-small cell lung cancer, whereas CD34, fibronectin, IDO1, lymphocyte-activation protein 3 (LAG3), arginase 1, and phosphatase and tensin homolog are significantly enriched in normal adjacent lung cancer tissues [28]. This evidence concerns the gene CD27 and lung cancer.