To clarify the association of PLK1 with immune infiltration, PLK1 expression was notably negatively associated with Stromal score, Immunes score, as well as Estimate score based on the ESTIMATE algorithm (Figs. 9B–9D), demonstrating that PLK1 promotes tumor progression mechanism may be strongly bound up with the inhibition of immune infiltration (Fig. 9A). This evidence concerns the gene PLK1 and neoplasm.