When compared to the transplanted tumor volume found in control group, the transplanted tumor volume found in Si-H1299 group (71.50 ± 52.08 mm3) was significantly lower (232.33 ± 67.25 mm3) (p < 0.001) (Figs. 12A–12C), which proved that PLK1 could promote the proliferation of LA, which was also confirmed by our study. This evidence concerns the gene PLK1 and neoplasm.