Sun et al. (2020) proposed that PVT1 promotes vascular endothelial cell proliferation by inhibiting miR-190a-5p, contributing to chronic heart failure. Researchers found increased PVT1 expression in peripheral blood monocytes of CAD patients (Nowrouzi-Sohrabi et al., 2022). Lu et al. (2021) reported that CASC8, CASC11 and PVT1 genetic polymorphisms were associated with the Gensini score in CAD patients. This evidence concerns the gene CASC8 and congestive heart failure.