BRAF and thyroid gland carcinoma: In our study, detected molecular aberrations were categorized into three MRGs: the BRAF-like group (presenting low differentiation and predominantly relevant to classical PTC with papillary architecture), the RAS-like group (displaying high differentiation, less recurrence, and enriched in thyroid carcinomas with follicular-pattern), and the high-risk group (relevant to poorly clinical outcomes and typically coexisting with other alterations) (Cancer Genome Atlas Research, 2014).