Furthermore, CAF subpopulations with similar characteristics and marker genes were identified in relapsed ovarian cancer (Figure 3E,F).[32] Based on the results of the pseudotime trajectory analysis, ICAM1+ iCAFs are likely to be derived from ICAM1‐iCAFs, and ICAM1+ iCAFs demonstrated high expression of genes such as TNFAIP6 and PTGS2 related to the inflammatory response, and AREG, a gene linked to tumor metastasis and drug resistance[33] (Figure S2DG, Supporting Information). This evidence concerns the gene AREG and ovarian carcinoma.