CRP and anemia (phenotype): In the joint effect analyses, compared to anemia-free participants with low CRP, the HR of dementia was 1.89 (95% CI 1.60, 2.22) among people with anemia and high CRP and 1.49 (1.23, 1.80) among those with anemia and low CRP (Fig. 2 and Supplementary Table 3).