DKK1 and coronary artery disorder: Similarly, the maximum likelihood analysis also supports DKK1 was a risk factor for CAD, with an OR of 1.090 (95% CI: 1.028-1.155; P = 0.003), as well as for IS, with an OR of 1.099 (95% CI: 1.011-1.195; P = 0.026).