Endometriosis is characterised by a progressive pelvic and systemic inflammation. Androgen receptors are present in endometriotic lesions. In vitro, testosterone has shown to reduce tissue inflammation through the significant reduction of pro-inflammatory cytokines and significant increase of anti-inflammatory cytokines. Ongoing studies are aimed at evaluating its anti-inflammatory and pro-sexual potential in vivo, in women with endometriosis and sexual pain disorders and associated FSD. Here, AR is linked to endometriosis.