ATP and soft agar experiments showed that LINC00955 fragments lacking the Sp1-binding domain, the TRIM25-binding domain, and both regions did not inhibit CRC cell proliferation (Fig. 7N–Q), which supported the conclusion that the function of LINC00955 depends on its binding to Sp1 and TRIM25. Here, LINC00955 is linked to colorectal carcinoma.