More interestingly, the expression of DSCC1 was positively correlated with multiple genetic mutations which drive cancer development, including TP53 (p = 1.3e-15), TTN (p = 9.3e-8), CSMD (p = 7.3e-6), ZFHX4 (p = 2.6e-6), COL11A1 (p = 6.6e-4), PCDH15 (p = 3.8e-4), XIRP2 (p = 5.1e-4), NAV3 (p = 5.9e-3), RYR2 (p = 1.3e-3), SPTA1(p = 2.4e-3), LRP1B (p = 4.8e-3), MUC16 (p = 9.0e-3) mutations (Fig. 1I) [30]. The gene discussed is RYR2; the disease is cancer.