MYCN and neuroblastoma: Differential expression analysis indicated that 1608 lncRNAs were upregulated and 1647 lncRNAs were downregulated in MYCN-amplified SK-N-DZ cells with the cut-off criteria of fold change > 2 and P < 0.05 (Fig. 1A), including lncNB1 (also known as RP1-40E16.9), AF127936.7 and RP11-102F4.3 that have been previously reported to be significantly increased in MYCN-amplified NB cell lines, which proved the robustness of our data to a certain extent [22].