IL17A and lung carcinoma: In mice with lung cancer, the combination of the polysaccharopeptide (PSP) and APS dramatically improved the level of WBC, thymus index, spleen index, CD4/CD8 ratio, TNF, IFN-γ, IL-2 and interleukin-17 (IL-17), which indicated their immunomodulatory effects and antitumor activity [107].