Statistically significant differences between the anemia of benign etiology group and bone marrow disease group were detected in EPO level (P < 0.001), red cell distribution width (RDW) (P < 0.001), mean corpuscular volume (MCV) (P < 0.001), Mean Corpuscular Hemoglobin Concentration (MCHC) (P = 0.014), ferritin (P < 0.001), transferrin saturation (P < 0.001), serum iron level (P < 0.001), and reticulocyte (P = 0.016) (Table 1). This evidence concerns the gene EPO and bone marrow disorder.