IGHE and gestational diabetes: Beneficial gut microbiota suppress neonatal food allergy by inducing expression of the transcription factor RORγt in Treg cells in a MyD88-dependent manner.55 Conversely, increased GATA3 expression and IL-4 secretion lead to dysregulated FA responses, dietary allergen-specific IgE responses, and impaired barrier integrity.56 This suggests that offspring with GDM are at higher risk of developing food allergies.