To further validate CDO1's tumour suppressive function, we employed CDO1 overexpression strategy in MDA‐MB‐231 and MCF‐7 cells, which demonstrated that CDO1 overexpression significantly inhibited cell proliferative, cell migrative and invasive capacities in vitro compared to the controls (Figure 3F–K, Figure S6). Here, CDO1 is linked to neoplasm.