CD74 and mantle cell lymphoma: To assess the sensitivity of MCL cells to 42105-74bbz CAR-T cells, we performed cytotoxicity assays in 6 CD74 positive MCL cell lines (JeKo-1, Mino, UPN-1, Granta-519, and Z138) and a CD74 negative T cell lymphoma cell line SUDHL1 as negative control (Fig. 3A).