Western blot results also showed that compared with the control group, the expression of Cleaved Caspase-3 and Bax increased significantly, while the expression of PI3K, p-AKT, Ras, p-Erk1/2, BCL-2, SNAP-25, and VGluT-1 decreased significantly in the HG and HG + HF + Exos groups. The gene discussed is AKT1; the disease is hydrops fetalis.