Due to their impacts on the malignant characteristics of HCC cells, some of candidate membrane proteins mentioned above like Annexin A2 (ANXA2), Filamin-A (FLNA), Moesin (MSN), Myosin-9 (MYH9), Elongation factor 2 (eEF2) and Tax1-binding Protein 3 (TAX1BP3) were further selected as the potential target proteins for future function analysis. Here, FLNA is linked to hepatocellular carcinoma.