Additional 70 proteins upregulated at both days 3 and 7 after infection in vitro, were upregulated in at least one organ in vivo, including DDX58, TAP2, OAS2, OAS3, PARP9, IFIT1, IFIT2, IFIT3, IFI16, STAT3, MX2, and others (see Supplementary Dataset 7). The gene discussed is STAT3; the disease is infection.