ITGB3 and melanoma: Several of the EMT-related genes with higher expression in NR patients encoded for molecules controlling adhesion (ITGB3, VCAM1, collagens, and others), interaction with extracellular matrix (VEGFA, MMP14, WNT5A, LAMA1, and others), and melanoma de-differentiation (KRT9, KRT10, EGFR, and others).