We found that although SCARB1 and CD36 also increased in HCC tissues compared to that in normal liver tissues (Supplementary Fig. 1j), only SCARB2 expression but not SCARB1 or CD36 was positively correlated with known CSC markers (EpCAM, CD24, CD133, or CD13) in HCC patients (Supplementary Fig. 1l). Here, SCARB1 is linked to hepatocellular carcinoma.