PROS1 and disseminated peritoneal leiomyomatosis: ,42 In response to LPD, we found that TJ protein CLD-3 was significantly reduced, and CLD-4 trended towards a reduction (p = 0.07, ANOVA with Tukey’s post-hoc comparison), while CLD-7 remained unchanged (Fig. 2b, d, Supplementary Fig. S2i–m).