Duration of follow-up, BMI, BMD at both LS and FN, and prevalence of T2D were comparable between patients with MACS and those without MACS, while size of the adenoma, prevalence of women, and prevalence of low ACTH levels was higher and ACTH levels were lower in the former than in the latter group (Table 3). Here, POMC is linked to type 2 diabetes mellitus.