A risk model based on XRCC4, XRCC5 and XRCC6 showed that the risk score was related to the prognosis, gender, clinical stage, T stage, lymph node metastasis and metastasis of LUAD patients and was an independent risk factor for the prognosis of LUAD patients [2]. This evidence concerns the gene XRCC5 and metastatic malignant neoplasm in the lymph nodes.