MORC2 and neoplasm: Conversely, NUDT21 silencing stimulated proliferation (Figure 9, F and G) and clonogenicity (Figure 9, F and H, and Supplemental Figure 6B) of KIRC cells, and this stimulation was relieved following MORC2 silencing, again supporting that NUDT21 acts as a tumor suppressor in KIRC through downregulating MORC2.