AFAP1L1 and neoplasm: To better comprehend the effect of AFAP1L1 on the tumor microenvironment, we loaded shAFAP1L1-Mus into adeno-associated viruses (AAV) under the control of the endothelial-specific promoter (TIE) (AFAP1L1-ECKD #1-#2) for subsequent in vivo experiments.