TP53 and breast cancer: We continued checking MCM4 expression in the TCGA BC and other TCGA datasets with TIMER2.0, which revealed that MCM4 expression was associated with MKI67 (Ki-67) (P < 0.0001) and EGFR (P < 0.0001), marginally significantly associated with TP53 (P = 0.0510), and inversely associated with FGFR3 gene expression (P < 0.0001) (Supplementary Fig. 2G-J).