We therefore investigated the relationship between MCM4 expression and various cancer-related molecules, including Ki-67, PD-L1 CD44v9, HER2, EGFR, FGFR3, p53, GATA3 and CK5/6 in 124 UTUC cases. This evidence concerns the gene TP53 and renal pelvis/ureter urothelial carcinoma.