MCM4 and renal pelvis/ureter urothelial carcinoma: MCM4-positive UTUC cases were associated with ages > 70 years (P = 0.0410), ureter UC (P = 0.0309), nodular/flat morphology (P = 0.0086), high tumor grade (P < 0.0001) and high pathological T stage (P < 0.0001) (Table 1).