FTO and Parkinson disease: Consistent with previous study [33], our study found that the total m6A level significantly decreased and the m6A demethylase FTO protein expression evidently increased in PD models using a MPTP-treated mice model and a MPP + -induced MN9D cellulal model, respectively, suggesting the dysregulation of m6A modification may be crucially involved in the pathogenesis of PD.